• Mohammad Ali Sahmeddini, TehranSamaneh GhazanfarSGAnesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. tehranisamaneh88rasht@gmail.com.Anesthesiology Research Center, Department of Anesthesiology, Alzahra Hospital, Guilan Universi, Mohammad Bagher Khosravi, Mohammad Hossein Eghbal, Naeimehossadat Asmarian, Fatemeh Khalili, Pooya Vatankhah, and Somayeh Izadi.
• Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
• BMC Anesthesiol. 2022 Apr 2; 22 (1): 89.

BackgroundPost reperfusion syndrome (PRS) is a relatively common and life-threatening complication during orthotopic liver transplantation (OLT). It is associated with poor patient and transplanted liver outcomes.ObjectiveThis study aimed to compare the risk factors of PRS during OLT.DesignClinical-epidemiological observational retrospective study.SettingWe gathered the records of patients who underwent OLT in 3 years, from May 22, 2016, to May 22, 2019, in Namazi and Bu-Ali Sina organ transplantation hospitals.PatientsIn this study, we assessed 1182 patients who underwent OLT. Patients were divided into two groups based on the presence or absence of PRS.Main Outcome MeasuresDiagnosing the predictors of PRS was the primary outcome of this study.ResultsResults showed that age > 60 years, Child-Pugh scores C, higher Model End Stage liver disease score, and preoperative sodium < 130 mmol/l (parameters of the liver recipient), increase in cold ischemic time (the donors' parameters), and the classical technique (the surgical parameters) were the strong predictors of PRS.ConclusionsThe results indicated that underlying liver disease was not the predictor of PRS in the presence of other risk factors; therefore, clinicians have to consider these risk factors in patients undergoing OLT.© 2022. The Author(s).

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