• Cleve Clin J Med · Mar 2018

    Review

    Acute cardiorenal syndrome: Mechanisms and clinical implications.

    • Guramrinder S Thind, Mark Loehrke, and Jeffrey L Wilt.
    • Department of Internal Medicine, Western Michigan University School of Medicine, Kalamazoo, MI, USA. guramrinder.thind@med.wmich.edu.
    • Cleve Clin J Med. 2018 Mar 1; 85 (3): 231-239.

    AbstractCardiac and renal dysfunction often coexist, and one begets the other. The association is referred to as cardiorenal syndrome. One subtype, acute cardiorenal syndrome, is often described as a clinical scenario in which acute worsening of cardiac function leads to acute kidney injury. Though this definition covers the basic pathophysiologic framework, a robust clinical definition is still lacking. Acute cardiorenal syndrome is common and often leads to emergency room visits and hospitalization. Our understanding of the hemodynamic mechanisms of acute cardiorenal syndrome is advancing. Correction of hypervolemia is the mainstay of therapy.Copyright © 2018 Cleveland Clinic.

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