• Shibao Fu, Zhibo Mo, Shuming He, Xianping Che, and Tingming Wu.
• Department of Urology Surgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan province, China.
• Medicine (Baltimore). 2022 Mar 11; 101 (10): e28898e28898.

BackgroundVarious nonpharmacological interventions have been applied to alleviate pain and improve sleep quality after percutaneous nephrolithotomy. However, evidence to compare their efficacy is scant. This study aims to evaluate the efficacy of different nonpharmacological interventions on alleviating pain and improving sleep quality in patients after percutaneous nephrolithotomy through a network meta-analysis .MethodsRandomized controlled trials reporting the efficacy of nonpharmacological interventions on alleviating pain and improving sleep quality in patients after percutaneous nephrolithotomy will be searched in online databases, including the Chinese Scientific Journal Database, China National Knowledge Infrastructure Database, Wanfang, China Biomedical Literature Database, Pubmed, Web of Science, Embase, and Cochrane Library. After quality assessment and date extraction, network meta-analysis will be performed using Stata 14.0 and R software.ResultsThe results of this meta-analysis will be submitted to a peer-reviewed journal for publication.ConclusionsThis study will provide systematic and comprehensive evidence-based support for the effects of nonpharmacological interventions on alleviating pain and improving sleep quality after percutaneous nephrolithotomy.Ethics And DisseminationEthical approval was not required for this study. The systematic review will be published in a peer-reviewed journal, presented at conferences, and shared on social media platforms.Registration NumberDOI 10.17605/OSF.IO/B4DHW.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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