• Eur. J. Clin. Invest. · Jul 2022

    "Obesities": Position Statement on a complex disease entity with multifaceted drivers.

    • Patricia Yárnoz-Esquiroz, Laura Olazarán, Maite Aguas-Ayesa, Carolina M Perdomo, Marta García-Goñi, Camilo Silva, José Antonio Fernández-Formoso, Javier Escalada, Fabrizio Montecucco, Piero Portincasa, and Gema Frühbeck.
    • Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.
    • Eur. J. Clin. Invest. 2022 Jul 1; 52 (7): e13811.

    AbstractAcademic medicine fosters research that moves from discovery to translation, at the same time as promoting education of the next generation of professionals. In the field of obesity, the supposed integration of knowledge, discovery and translation research to clinical care is being particularly hampered. The classification of obesity based on the body mass index does not account for several subtypes of obesity. The lack of a universally shared definition of "obesities" makes it impossible to establish the real burden of the different obesity phenotypes. The individual's genotype, adipotype, enterotype and microbiota interplays with macronutrient intake, appetite, metabolism and thermogenesis. Further investigations based on the concept of differently diagnosed "obesities" are required.© 2022 The Authors. European Journal of Clinical Investigation published by John Wiley & Sons Ltd on behalf of Stichting European Society for Clinical Investigation Journal Foundation.

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