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- Rudolf Arnold.
- Klinik für Innere Medizin, Schwerpunkt Gastroenterologie und Endokrinologie, Klinikum Giessen-Marburg, Standort Marburg, Philipps Universität, Marburg, Germany. arnoldr@mailer.uni-marburg.de
- Wien. Klin. Wochenschr. 2007 Jan 1; 119 (19-20): 564-9.
AbstractThe most frequent conditions of hypergastrinemia in man are the Zollinger-Ellison syndrome with autonomous gastrin hypersecretion by the tumour cell and reactive hypergastrinemia in type A autoimmune chronic atrophic gastritis with achlorhydria causing unrestrained gastrin release from the gastrin-producing antral G-cells. Both entities differ with respect to the pH in the gastric fluid, which is < 2 in patients with Zollinger-Ellison syndrome and neutral in type A gastritis. Other conditions with moderate hypergastrinemia as treatment with proton pump inhibitors, gastric outlet obstruction, previous vagotomy, chronic renal failure or short bowel syndrome are of minor clinical importance.
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