• Ups. J. Med. Sci. · Jan 2022

    Review

    Molecular tools to monitor health and disease - and lucky coincidences.

    • Ulf Landegren.
    • Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
    • Ups. J. Med. Sci. 2022 Jan 1; 127.

    AbstractImproved methods for molecular analyses are obviously central for medical research. I will describe herein our work developing tools to reveal molecular states in health and disease. I will recount how I got started in this endeavor, and how our early work characterizing genetic variation led onto high-throughput protein measurements and to techniques for imaging the distribution of proteins and their activity states in tissues. I will also describe a more recent technique to measure even exceedingly rare genetic variants in order to monitor recurrence of disease for tumor patients.© 2022 The Author(s). Published by Upsala Medical Society.

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