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- Vanessa R Salasky and ChangWan-Tsu WWWDepartments of Emergency Medicine and Neurology, Program in Trauma, University of Maryland School of Medicine, 22 South Greene Street, G7K18, Baltimore, MD 21201, USA. Electronic address: wchang1@som.umaryland.edu..
- Department of Neurology, Section of Neurocritical Care and Emergency Neurology, University of Maryland Medical Center, 22 South Greene Street, G7K18, Baltimore, MD 21201, USA.
- Emerg. Med. Clin. North Am. 2023 Feb 1; 41 (1): 193319-33.
AbstractTraumatic brain injury (TBI) continues to be a leading cause of morbidity and mortality worldwide with older adults having the highest rate of hospitalizations and deaths. Management in the acute phase is focused on preventing secondary neurologic injury from hypoxia, hypocapnia, hypotension, and elevated intracranial pressure. Recent studies on tranexamic acid and continuous hypertonic saline infusion have not found any difference in neurologic outcomes. Care must be taken in prognosticating TBI outcomes, as recovery of consciousness and orientation has been observed up to 12 months after injury.Copyright © 2022 Elsevier Inc. All rights reserved.
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