• Croatian medical journal · Jun 2009

    Genetic polymorphisms of 17 Y-chromosomal short tandem repeat loci in Atayal population of Taiwan.

    • Fang-Chin Wu, Chin-Wen Ho, Chang-En Pu, Kuang-Yu Hu, and David Hwang Liu.
    • Department of Bioengineering, Tatung University, No. 40 Chungshan N. Rd. Sec. 3, Taipei City 104, Taiwan, R.O.C.
    • Croat. Med. J. 2009 Jun 1; 50 (3): 313320313-20.

    AimTo define the Y-chromosomal genetic structure in a sample of Atayal men from Taiwan.MethodsBuccal swab samples were collected from 170 unrelated healthy male volunteers from Taiwanese aboriginal Atayal population. Genomic DNA was extracted and 17 Y chromosome-specific short tandem repeat loci (DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4, DYS437, DYS438, and DYS448) were analyzed using the AmpFlSTR Yfiler Polymerase Chain Reaction Amplification Kit.ResultsA total of 99 different haplotypes were identified, 69 (69.7%) of which were unique. Total haplotype diversity was 0.9887. The most common haplotype was shared by 9 individuals in the study sample. Gene diversities ranged from 0.0574 for DYS438 to 0.6749 for DYS456.ConclusionOur results will help provide the molecular genetic evidence for human settlement of the Pacific.

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