• Am. J. Med. Sci. · Nov 1986

    Case Reports

    HTLV-I-associated T-cell leukemia in Hawaii.

    • M Yim, T Hayashi, E Yanagihara, M Kadin, and J Nakamura.
    • Am. J. Med. Sci. 1986 Nov 1; 292 (5): 325327325-7.

    AbstractAdult T-cell leukemia (ATL) is a disease found endemic in Southern Japan and the Caribbean basin. The human T-cell leukemia virus I (HTLV-I) has been implicated epidemiologically as the causative agent in this disease. This paper describes the identification of this disease in Hawaii in a second generation immigrant from Southern Japan. The disease was initially indolent, then clinically explosive, characterized by cutaneous lesions, leukemic lymphocytes with convoluted nuclei of T-cell phenotype, hypercalcemia, and a terminal infection.

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