• Emerg. Med. Clin. North Am. · Feb 1995

    Review

    Tuberculosis in the HIV-infected patient.

    • S Waxman, M Gang, and L Goldfrank.
    • Department of Emergency Medicine, Bellevue Hospital Center, New York, New York.
    • Emerg. Med. Clin. North Am. 1995 Feb 1; 13 (1): 179198179-98.

    AbstractAfter decades of decline, tuberculosis has emerged as a global health challenge. In the setting of HIV immunocompromise, TB occurs frequently, early, and often atypically. New infections can take an accelerated course. The usual tests for diagnosing Mycobacterium tuberculosis infection are less sensitive when CD4+ counts are low. Increased prevalence of treatment failure, drug-resistant strains, and nosocomial transmission of multidrug-resistant TB are discussed as are new diagnostic tests that will accelerate the time to diagnosis and allow better epidemiologic tracking. Early recognition, isolation, appropriate therapy, and environmental controls that will protect staff and patients from the risk of exposure are also described.

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