• Seung Won Choi, Sogu Lew, Sung Do Cho, Hee Jeong Cha, Eun A Eum, Hyun Chul Jung, and Jae Hoo Park.
• Department of Internal Medicine, Ulsan University Hospital, College of Medicine, University of Ulsan, Dong-gu, Ulsan, Korea. choisw@uuh.ulsan.kr
• J. Korean Med. Sci. 2006 Apr 1; 21 (2): 371373371-3.

AbstractCutaneous polyarteritis nodosa (CPAN) is an uncommon form of vasculitis involving small and medium sized arteries of unknown etiology. The disease can be differentiated from polyarteritis nodosa by its limitation to the skin and lack of progression to visceral involvement. The characteristic manifestations are subcutaneous nodule, livedo reticularis, and ulceration, mostly localized on the lower extremity. Arthralgia, myalgia, peripheral neuropathy, and constitutional symptoms such as fever and malaise may also be present. We describe a 34-yr-old woman presented with severe ischemic change of the fingertip and subcutaneous nodules without systemic manifestations as an unusual initial manifestation of CPAN. Therapy with corticosteroid and alprostadil induce a moderate improvement of skin lesions. However, necrosis of the finger got worse and the finger was amputated.

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