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J. Korean Med. Sci. · Nov 2018
ReviewPsychiatric Manifestation in Patients with Parkinson's Disease.
- Ji Won Han, Yebin D Ahn, Won-Seok Kim, Cheol Min Shin, Seong Jin Jeong, Yoo Sung Song, Yun Jung Bae, and Jong-Min Kim.
- Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Korea.
- J. Korean Med. Sci. 2018 Nov 19; 33 (47): e300e300.
AbstractParkinson's disease (PD) is the second most common neurodegenerative disorder. Although its major manifestation is motor symptoms, resulting from the loss of dopaminergic neurons in the substantia nigra, psychiatric symptoms, such as depression, anxiety, hallucination, delusion, apathy and anhedonia, impulsive and compulsive behaviors, and cognitive dysfunction, may also manifest in most patients with PD. Given that the quality of life - and the need for institutionalization - is so highly dependent on the psychiatric well-being of patients with PD, psychiatric symptoms are of high clinical significance. We reviewed the prevalence, risk factors, pathophysiology, and treatment of psychiatric symptoms to get a better understanding of PD for improved management.
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