• Alberto R Ramos, Douglas M Wallace, Seithikurippu Ratnas Pandi-Perumal, Natasha J Williams, Chimene Castor, Mary Ann Sevick, Samy I Mcfarlane, and Girardin Jean-Louis.
• Department of Neurology, Miller School of Medicine, University of Miami , Miami , FL, USA.
• Ann. Med. 2015 May 1; 47 (3): 233237233-7.

IntroductionThe association between sleep disturbances and cardiometabolic diseases has been understudied in blacks with metabolic syndrome.MethodsThis study is a cross-sectional analysis of the Metabolic Syndrome Outcome Study (MetSO) trial. We assessed insomnia symptoms, sleep duration, and risk for sleep apnea. Multivariate logistic regression models evaluated the association between sleep disturbances with diabetes mellitus (DM) and the combined outcomes of DM and hypertension as well as DM and dyslipidemia.ResultsThe sample consisted of 1,013 participants, mean age of 62 ± 14 years and 61% female. DM was diagnosed in 60% of the sample. Sleep apnea risk was observed in 48% of the sample, while 10% had insomnia symptoms and 65% reported short sleep duration (< 6 hours). Sleep apnea risk, but not insomnia or sleep duration, was associated with DM (OR 1.66; 95% CI 1.21-2.28), adjusting for age, sex, income, obesity (BMI ≥ 30 kg/m(2)), tobacco use, alcohol use, hypertension, dyslipidemia, and depression. In fully adjusted models, sleep apnea risk was associated with the combined outcome of DM-hypertension (OR 1.95; 95% CI 1.42-2.69), but not with diabetes-dyslipidemia.ConclusionWe observed a strong association between sleep apnea risk and diabetes mellitus among blacks with metabolic syndrome.

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