• Semin Respir Crit Care Med · Feb 2023

    Techniques for Oxygenation and Ventilation in Coronavirus Disease 2019.

    • Guy A Richards and Oliver Smith.
    • Department of Critical Care, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg South Africa.
    • Semin Respir Crit Care Med. 2023 Feb 1; 44 (1): 919991-99.

    AbstractThis paper discusses mechanisms of hypoxemia and interventions to oxygenate critically ill patients with COVID-19 which range from nasal cannula to noninvasive and mechanical ventilation. Noninvasive ventilation includes continuous positive airway pressure ventilation (CPAP) and high-flow nasal cannula (HFNC) with or without proning. The evidence for each of these modalities is discussed and thereafter, when to transition to mechanical ventilation (MV). Various techniques of MV, again with and without proning, and rescue strategies which would include extra corporeal membrane oxygenation (ECMO) when it is available and permissive hypoxemia where it is not, are discussed.Thieme. All rights reserved.

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