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Semin Respir Crit Care Med · Feb 2023
ReviewUse of Antiviral Agents and other Therapies for COVID-19.
- Mark A T Blaskovich and Anthony D Verderosa.
- Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.
- Semin Respir Crit Care Med. 2023 Feb 1; 44 (1): 118129118-129.
AbstractThe coronavirus disease 2019 (COVID-19) pandemic led to a remarkably rapid development of a range of effective prophylactic vaccines, including new technologies that had not previously been approved for human use. In contrast, the development of new small molecule antiviral therapeutics has taken years to produce the first approved drugs specifically targeting severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), with the intervening years filled with attempts to repurpose existing drugs and the development of biological therapeutics. This review will discuss the reasons behind this variation in timescale and provide a survey of the many new treatments that are progressing through the clinical pipeline.Thieme. All rights reserved.
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