• Anesthesiology clinics · Dec 2012

    Review

    Perioperative oxygen toxicity.

    • Andrew B Lumb and Laura J Walton.
    • Department of Anaesthesia, St James's University Hospital, Leeds, United Kingdom. a.lumb@leeds.ac.uk
    • Anesthesiol Clin. 2012 Dec 1;30(4):591-605.

    AbstractThis article challenges the use of hyperoxia in the perioperative period. It describes the biochemical and physiologic basis for both the direct and indirect adverse effects of oxygen. The reasons for using hyperoxia in the perioperative period are critically evaluated, and the evidence and guidelines for oxygen use in common acute medical conditions are reviewed.Copyright © 2012 Elsevier Inc. All rights reserved.

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