• Cleve Clin J Med · Aug 2023

    Review

    Evaluating troponin elevation in patients with chronic kidney disease and suspected acute coronary syndrome.

    • Lorenzo Braghieri, Osamah Z Badwan, Warren Skoza, Maan Fares, and Venu Menon.
    • Department of Internal Medicine, Cleveland Clinic, Cleveland, OH braghil@ccf.org.
    • Cleve Clin J Med. 2023 Aug 1; 90 (8): 483489483-489.

    AbstractMany patients with chronic kidney disease have chronically elevated cardiac troponin levels, and if they present with symptoms suggesting an acute coronary syndrome, it is often difficult to determine if this is the correct diagnosis. This article briefly reviews the major challenges in diagnosing acute coronary syndrome in patients with chronic kidney disease, describes the mechanisms and prognostic significance of troponin elevation in chronic kidney disease, and provides a diagnostic algorithm to risk-stratify patients with chronic kidney disease who have troponin elevation and suspected acute coronary syndrome.Copyright © 2023 The Cleveland Clinic Foundation. All Rights Reserved.

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