• Annals of Saudi medicine · Jul 2023

    Management of twin reversed arterial perfusion sequence: eight cases over 13 years.

    • Saud Alshanafey, Maha Al-Nemer, Maha Tulbah, Rubina Ma Khan, SahanNada AlNAFrom the Department of Obstetrics and Gynecology Perinatology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., MugbelMaisoon AlMAFrom the Department of Obstetrics and Gynecology Perinatology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Fahad Al-Hazzani, Gawaher Almutairi, and Wesam Kurdi.
    • From the Department of Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
    • Ann Saudi Med. 2023 Jul 1; 43 (4): 199203199-203.

    BackgroundTwin reversed arterial perfusion (TRAP) sequence is a rare condition that affects primarily monozygotic monochorionic twin pregnancies in which a normal twin acts as a pump (donor) for an acardiac recipient (perfuse) twin.ObjectiveWe report our experience over the last 13 years at a tertiary health care center.DesignDescriptive, retrospective case series SETTING: Tertiary health care center PATIENTS AND METHODS: All TRAP cases managed between the years 2009 and 2022 at our Fetal Diagnosis and Therapy Center were included. Data recorded included demographic and clinical information which was used to generate descriptive data. Patients were managed by a multidisciplinary team with variable interventions.Main Outcome MeasureSurvival of normal twin SAMPLE SIZE: Eight RESULTS: Eight pregnant women with TRAP syndrome were managed at our center during that period. One was monozygotic monochorionic and the others were monochorionic diamniotic. Median maternal age at presentation was 27 years and median gestational age at diagnosis was 23 weeks. All were diagnosed with ultrasound (US) imaging. Three were managed with bipolar ligation of the cord of the acardiac twin under general anesthesia, one US-guided (single port) and 2 fetoscopic (2 ports) with a median operative time of 39 minutes. The last five cases were managed with US-guided radiofrequency ablation (RFA) under local anesthesia, one needed 2 sessions, 1 week apart. The median duration of the RFA procedure was 23 minutes. There were no complications and all had viable normal babies born at a median of 32 weeks of gestation (6 C-section, 2 spontaneous membrane rupture).ConclusionsAcardiac twin cord ligation and RFA are feasible and safe options with excellent outcome for TRAP syndrome. RFA may be preferable owing to its less invasiveness under local anesthesia.LimitationsNone, given the rarity of the disease and the study design.Conflict Of InterestNone.

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