• Saudi Med J · Oct 2023

    Case Reports

    Macrophage activation syndrome induced by Staphylococcus Epidermidis in a pediatric patient with cystic fibrosis and familial Mediterranean fever.

    • Sanem Eryilmaz Polat, Salih Uytun, Işıl Bilgiç, and Gokcen D Tuğcu.
    • From the Department of Pediatrics, Division of Pediatric Pulmonology, Ankara City Hospital, Ankara, Turkey.
    • Saudi Med J. 2023 Oct 1; 44 (10): 106110641061-1064.

    AbstractStaphylococcus epidermidis (S. epidermidis) is the most frequently isolated member of the coagulase-negative staphylococci, which colonizes the skin and mucous membranes of the human body. Despite being a component of the normal flora, S. epidermidis can act as an opportunistic pathogen and is frequently implicated in both bacterial and nosocomial infections. Macrophage activation syndrome (MAS) is a rare but potentially fatal disease that occurs as a result of increased activation and proliferation of T lymphocytes and macrophages in response to infections and immune mediated diseases. It is very rare in patients with cystic fibrosis. Here we report a case of an 8-year-old girl with cystic fibrosis and familial Mediterranean fever who developed MAS after contracting a S. epidermidis infection.Copyright: © Saudi Medical Journal.

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