• Aiping Zhou, Ying Wang, Yanling Chen, Hua Zhong, Bo Chen, and Chunyu Tan.
• West China School of Nursing, Sichuan University/Department of Rheumatism and Immunology, West China Hospital, Sichuan University, Chengdu, China.
• Medicine (Baltimore). 2023 Oct 13; 102 (41): e35374e35374.

RationaleLimited literatures are available on lower gastrointestinal bleeding in systemic lupus erythematosus (SLE) combined with intestinal tuberculosis. Sharing the treatment experiences of a 26-year-old female patient diagnosed with this complex condition in this report may contribute valuable insights.Patient ConcernsThe patient initially presented with abdominal pain and active gastrointestinal bleeding, leading to admission to the hospital. Over a 2-week period, she experienced persistent bleeding, with daily volumes ranging from 300 mL to 800 mL.DiagnosesLower gastrointestinal bleeding was diagnosed in this patient with concurrent systemic lupus erythematosus and intestinal tuberculosis.InterventionsAs her symptoms rapidly progressed, food and water intake had to be completely restricted. The parenteral nutrition was implemented.OutcomesThe medical team effectively controlled the bleeding, leading to a notable improvement in the patient's condition. Consequently, she was able to resume oral intake and was discharged from the hospital.LessonsThis case highlights the significance of using parenteral nutrition in the management of lower gastrointestinal bleeding in patients with concurrent systemic lupus erythematosus and intestinal tuberculosis. Close monitoring and collaborative efforts among healthcare professionals are crucial to achieve successful outcomes in similar cases.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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