• Muhammad Sajid Rafiq Abbasi, Khawar Sultan, Rukhsana Manzoor, Awais Ahmad Nizami, Naeem Ullah, Adnan Mushtaq, Humayun Saleem, Qudsia Umaira Khan, Amna Akbar, Khan JadoonSaroshSResident Surgeon SKBZ/CMH, Muzaffarabad AJK, Pakistan., Sabahat Tasneem, Mohammad Saleem Khan, and Sarosh Alvi.
• FRCP Glasgow UK, Department of Nephrology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan.
• Medicine (Baltimore). 2023 Oct 20; 102 (42): e35482e35482.

AbstractAcute kidney injury (AKI) is a sudden decline in renal function after cardiac surgery. It is characterized by a significant reduction in glomerular filtration rate, alterations in serum creatinine (S.Cr) levels, and urine output. This study aimed to retrospectively analyze a cohort of 704 patients selected using stringent inclusion and exclusion criteria. AKI was defined by an increase of 0.3 mg/dL in S.Cr levels compared to baseline. Data were collected from the hospital and analyzed using SPSS 16.0. Data analysis revealed that 22% (n = 155) of the patients developed AKI on the second post-operative day, accompanied by a substantial increase in S.Cr levels (from 1.064 ± 0.2504 to 1.255 ± 0.2673, P < .000). Age and cardiopulmonary bypass duration were identified as risk factors along with ejection fraction and days of hospital stay, contributing to the development of AKI. Early renal replacement therapy can be planned when the diagnosis of AKI is established early after surgery.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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