• Med Klin · Jul 1990

    Randomized Controlled Trial Clinical Trial

    [Neopterin as a marker of aspecific immunostimulation with Propionibacterium avidum KP-40 in patients with gastrointestinal tumors. A prospective randomized study].

    • K M Peters, B Bornhofen, R Grundmann, H L Ko, J Beuth, W Waters, H Pichlmaier, and G Pulverer.
    • Orthopädische Klinik der Medizinischen Fakultät der RWTH Aachen.
    • Med Klin. 1990 Jul 15; 85 (7): 421424421-4.

    AbstractThis prospective randomized study demonstrated that a preoperative intravenous infusion of 10 mg of the bacterial preparation Propionibacterium avidum KP-40 to patients with gastrointestinal tumors significantly (P less than 0.001) enhanced the secretion of neopterin, measurable as long-lasting (greater than 16 days) elevated urine excretion. Postoperative re-infusion of P. avidum KP-40 caused (statistically significant (p less than 0.001] re-enhancement of neopterin urine levels.

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