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- Sindhuja Nimma, Asaf Gans, Richa Wardhan, and Wesley Allen.
- From the Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Jacksonville, Florida.
- A A Pract. 2023 Dec 1; 17 (12): e01733e01733.
AbstractAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease involving the upper and lower motor neurons. Perioperative management of patients with ALS can be challenging due to the risk of hemodynamic instability, aspiration, and ventilatory failure. We discuss a 58-year-old male patient with ALS who underwent open abdominal surgery under regional anesthesia utilizing a remimazolam infusion for sedation. While various sedation agents have been used successfully in patients with ALS, remimazolam, a new short-acting benzodiazepine with unique pharmacologic properties and reversible anxiolysis, provides amnesia while avoiding ventilatory depression.Copyright © 2023 International Anesthesia Research Society.
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