• Mohammed Y Elamin, Yahya A Maslamani, Feras A Alsheikh, Mohsen A Sailah, Mussab A Samm, Ahmed M Motanbk, Yehya M Hejri, Anwar A Alameer, Osama H Khalid, Abdu A Dahlan, and Ibrahim M Gosadi.
• From the Public Health Administration (Elamin, Maslamani, Alsheikh, Sailah, Hejri, Alameer, Khalid, Dahlan); from the Command and Control Center (Samm); from the Emergency Administration (Motanbk), Jazan Health Directorate, and from the Department of Family and Community Medicine (Gosadi), Faculty of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.
• Saudi Med J. 2024 Feb 1; 45 (2): 179187179-187.

ObjectivesTo evaluate the impact of coronavirus disease-19 (COVID-19) vaccination on morbidity and mortality in adults hospitalized with COVID-19 during the omicron wave in the Jazan Region, Saudi Arabia.MethodsA 6-month record-based historical prospective study enrolled COVID-19 adult patients admitted between January and June 2022. Individuals were classified into 3 groups according to their immunity status (immunized, partially immunized, and not immunized). Death, intensive care unit (ICU) admission, and mechanical ventilation were identified as the primary outcomes, collectively referred to as "serious outcomes". On the other hand, the length of hospital stays longer than 5 days was categorized as a secondary outcome. Multiple logistic regression analysis was used to evaluate independent factors and the relationship between the outcomes and vaccination status.ResultsAmong the 634 COVID-19 patients admitted to Jazan hospitals, 46.4% were fully immunized, 19.7% were partially immunized, and 33.9% were not immunized. Not being immunized was significantly associated with ICU admission (odds ratio [OR]=1.91, 95% confidence interval [CI]: [1.17-3.11]; p=0.009), mechanical ventilation (OR=2.11, 95% CI: [1.25-3.56]; p=0.005), increased length of hospital stays (OR=1.79, 95% CI: [1.24-2.59]; p=0.002), and death (OR=3.03, 95% CI: [1.85-4.98]; p<0.001).ConclusionOur study underscores the importance of a comprehensive approach for managing COVID-19 patients that includes vaccination against the disease.Copyright: © Saudi Medical Journal.

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