• Xiao Liu, Yuanda Zhang, Qingwei Dong, Hongyu Deng, and Jing Bi.
• Xiao Liu, Department of Gastroenterology, Beijing Children's Hospital Affiliated to Capital Medical University Baoding Hospital, Baoding, Hebei,071000, P.R. China. Key Laborary of Clinical, Research on Respiratory Digestive Disease, Hebei Baoding, 071000, China.
• Pak J Med Sci. 2024 Mar 1; 40 (4): 674678674-678.

ObjectiveTo explore the correlation of iron deficiency (ID) indexes with eradication and recurrence of Helicobacter pylori (Hp) infection in children.MethodsThis is a clinical comparative study. One hundred and twenty-six children who were first diagnosed as Hp infection in Baoding Children's Hospital (Hp infection group); and the control group included 200 children without Helicobacter Pylori infection (negative stool Hp antigen test and/or 13C-urea breath test) in local region at the same time from January 2020 to January 2022. Enrolled children were subjected to routine blood test, serum ferritin (SF), serum iron (SI) and total iron binding capacity (TIBC) detection. Meanwhile, children with Hp infection were given triple therapy for eradication and followed up for one year.ResultsThe levels of SI, SF and Hb in non-eradication group were lower than those in eradication group (P<0.05); while TIBC level in the former group was higher than that in the latter group (P<0.05). Furthermore, SF level in the recurrence group was lower than that in the non-recurrence group (P<0.05). While there was no significant difference in Hb, SI and TIBC levels between the recurrence group and the non-recurrence group (P>0.05).ConclusionLow level of SF may be a risk factor for difficulty in eradication and recurrence after eradication in children with Hp infection. Meanwhile, low levels of Hb and SI are influential factors for difficulty in eradication in children with Hp infection.Copyright: © Pakistan Journal of Medical Sciences.

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