• Pak J Med Sci · Mar 2024

    Case Reports

    Young-onset dementia following chronic abuse of amphetamine-type stimulants.

    • Sultan H Alamri.
    • Sultan H. Alamri, MBBS Department of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
    • Pak J Med Sci. 2024 Mar 1; 40 (4): 779781779-781.

    AbstractYoung-onset dementia (YOD) is influenced by various risk factors, including substance abuse. In this report, we present the case of a 54-year-old man who developed YOD following prolonged abuse of amphetamine-type stimulants. The patient exhibited insidious cognitive decline over a three-year period before seeking medical attention. Neuroimaging revealed atrophy of the temporal lobe, suggesting a connection between amphetamine-induced neurotoxicity and the cognitive abnormalities observed in the patient condition. Our case highlights the importance of considering amphetamine-type stimulants as potential risk factors for YOD and emphasizes the need to recognize cognitive impairment resulting from substance abuse. Additionally, we look into relevant literature to provide further context and insights.Copyright: © Pakistan Journal of Medical Sciences.

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