• J Res Med Sci · Mar 2013

    The relationship between serum levels of vitamin D and migraine.

    • Tayebeh Mottaghi, Fariborz Khorvash, Gholamreza Askari, Mohammad Reza Maracy, Reza Ghiasvand, Zahra Maghsoudi, and Bijan Iraj.
    • Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
    • J Res Med Sci. 2013 Mar 1; 18 (Suppl 1): S66S70S66-70.

    BackgroundMigraine is common worldwide. In recent years, vitamin D deficiency has been determined as a global health problem. A few studies have shown inverse relationship between serum vitamin D levels and headache. Thus, in this study, we assessed relationship between serum vitamin D levels with migraine.Materials And MethodsThe present study was a cross-sectional. Seventy-six migraine patients aged 10-61 years were included. The multiple linear regression was used to show association between serum 25-0H-D3 and migraine. Adjustments were performed for age, sex, waist circumference, body mass index (BMI), number of chronic diseases, and education level.ResultsThe positive weak relationship was observed between serum vitamin D and headache diary result (P = 0.042, r = 0.19). But, no significant relationship was observed between serum vitamin D and migraine severity (P = 0.741).ConclusionHigh levels of serum 25-OH-D3 was related to higher headache diary result. After adjustment for confounding variables, this significant association remained. No significant relationship was shown between serum vitamin D and migraine severity.

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