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Review
A review on associated factors and management measures for sarcopenia in type 2 diabetes mellitus.
- Yi Zhang, Kemeng Zhang, Sui Huang, Wenhan Li, and Ping He.
- Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
- Medicine (Baltimore). 2024 Apr 19; 103 (16): e37666e37666.
AbstractType 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by hyperglycemia, insulin resistance, and insufficient insulin secretion. Sarcopenia, as a new complication of diabetes, is characterized by the loss of muscle mass and the progressive decline of muscle strength and function in T2DM patients, which has a serious impact on the physical and mental health of patients. Insulin resistance, mitochondrial dysfunction, and chronic inflammation are common mechanisms of diabetes and sarcopenia. Reasonable exercise training, nutrition supplement, and drug intervention may improve the quality of life of patients with diabetes combined with sarcopenia. This article reviews the relevant factors and management measures of sarcopenia in T2DM patients, in order to achieve early detection, diagnosis, and intervention.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.
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