• Erin Peacock, Paul Muntner, Leslie S Craig, Julia Silver, Katherine T Mills, Jing Chen, Lizheng Shi, Paul K Whelton, Jiang He, and Marie Krousel-Wood.
• Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA; Center for Health Outcomes, Implementation, and Community-Engaged Science, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA. Electronic address: epeacoc@tulane.edu.
• Med. Clin. North Am. 2023 Nov 1; 107 (6S): e39e52e39-e52.

AbstractUncontrolled hypertension and low antihypertensive medication adherence remain significant clinical challenges. There is a critical need to detect meaningful change in adherence in clinical settings. The authors determined that a ≥2-point change in the 4-item Krousel-Wood Medication Adherence Scale score represents meaningful change in antihypertensive medication adherence. Among a sample of participants in an ongoing clinical trial, 5.9% experienced a decline in adherence, which was associated with higher blood pressure (BP) and a higher prevalence of uncontrolled BP at 6 months. Meaningful change in medication adherence behavior may be key in managing hypertension to improve BP control and health outcomes.Copyright © 2023 Elsevier Inc. All rights reserved.

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