• Eduardo M Warley, Norma Heine, Pablo Garnica, Federico Rojas, Byron Castañeda, Ainoha Vilariño, Melisa Saboundji, María Inés Vieni, Sonia Mores, and Silvina Tavella.
• Unidad de Infectología, Hospital Dr. Diego Paroissien, Isidro Casanova, Buenos Aires, Argentina. E-mail: eduwarley@yahoo.com.ar.
• Medicina (B Aires). 2024 Jan 1; 84 (2): 249255249-255.

IntroductionCombined prevention (CP) is considered the key strategy against the HIV epidemic. The objective of the study was to evaluate the perception of risk of HIV infection and the knowledge about the use of antiretrovirals (ARV) for prevention, among patients who attend a Sexually Transmitted Infections (STI) clinic.MethodsA survey on personal data and perception of risk of HIV infection, knowledge about post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP), was administered to patients at the time of applying doses of penicillin for the treatment of syphilis, or when taking a blood sample for STI diagnosis, between May and December, 2022.Results100 persons were surveyed: 43 were under 25 years of age, 67 reported male sex-gender and 33 females. Thirty of 91 (33%) perceived they had had some risk of infection in their lives, 19 of them in the last year; 77/96 (80%) stated that they had no knowledge about PEP, and 82/100, about PrEP. Only 22 out of 100 responded that antiretrovirals could provide benefit in preventing HIV; 26 (60%) of the 43 patients <25 years of age, and 18 of the 57 ≥ 25 years (31.6%) responded they have had two or more sexual partners in the last year. No statistically significant differences were observed related to gender and age group.DiscussionThe low perception of infection risk and knowledge about the use of antiretrovirals in HIV prevention, show the existing difficulties for the implementation of combined prevention (PEP-PrEP) in this population.

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