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J. Korean Med. Sci. · Jun 2004
Case ReportsWidespread scleredema accompanied with a monoclonal gammopathy in a patient with advanced ankylosing spondylitis.
- Hyun Kyu Chang, You Chan Kim, and Bum Sun Kwon.
- Division of Rheumatology, Department of Internal Medicine, Dankook University Hospital, Cheonan, Korea. hanks22@dankook.ac.kr
- J. Korean Med. Sci. 2004 Jun 1; 19 (3): 481483481-3.
AbstractScleredema is a rare cutaneous mucinosis characterized by chronic diffuse induration of the skin, and it is occasionally associated with a monoclonal gammopathy (MG). Ankylosing spondylitis (AS) is noted to be another, chronic systemic inflammatory disorder of the axial skeleton that may accompany the MG. However, patients with scleredema and AS accompanied with a MG have not been reported in the literature. We here report a 40-yr-old man with scleredema and advanced AS accompanied with a MG of IgA-kappa protein. Widespread, long-standing scleredema has been developed over 10 yrs after the initial manifestation of AS. It is uncertain whether the coexistence of scleredema and AS is more than coincidental.
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