• Ann. Intern. Med. · May 2024

    Comment Randomized Controlled Trial

    In older patients with AF and frailty, switching from VKA to NOAC therapy increased a composite of major or CRNM bleeding at 12 mo.

    • Andrew Dunn.
    • Icahn Mount Sinai School of Medicine, New York, NY, USA (A.D.).
    • Ann. Intern. Med. 2024 May 1; 177 (5): JC57JC57.

    AbstractJoosten LP, van Doorn S, van de Ven PM, et al. Safety of switching from a vitamin K antagonist to a non-vitamin K antagonist oral anticoagulant in frail older patients with atrial fibrillation: results of the FRAIL-AF randomized controlled trial. Circulation. 2024;149:279-289. 37634130.

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