• Am. J. Med. Sci. · Sep 2024

    Review Case Reports

    Cryptosporidium-induced acute kidney injury in a patient with acquired immunodeficiency syndrome.

    • Yi-Hsin Chou and Hung-Ju Fan.
    • Division of Nephrology, Taipei City Hospital Zhongxing Branch, Taiwan; School of Medicine, National Yang Ming Chiao Tung University, Taiwan. Electronic address: DBD58@tpech.gov.tw.
    • Am. J. Med. Sci. 2024 Sep 1; 368 (3): 253257253-257.

    AbstractCryptosporidium is a pathogen that can cause infectious enteritis especially in immunocompromised patients. Acute kidney injury, electrolyte imbalance, and acid-base disorders may occur as a result of high volumes of intestinal fluid loss, which has not been previously reported to be a common manifestation of cryptosporidiosis. Numerous antigen detection methods can be used to ensure early diagnosis of Cryptosporidium infection, which is crucial to prevent morbidities. We report a unique case of cryptosporidiosis in a 33-year-old male patient with acute kidney injury and profound hypokalemia, hyponatremia, hypocalcemia, hypophosphatemia, hypomagnesemia, and metabolic acidosis. Following the initiation of antiretroviral therapy to human immunodeficiency virus, the patient's symptoms improved and he recovered fully from kidney injury and electrolyte imbalance, highlighting the importance of early antiretroviral therapy.Copyright © 2024 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

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