• Mingliang Shao, Chenhuan Yao, Yafan Han, Xianhui Zhou, Yanmei Lu, Ling Zhang, Yaodong Li, and Baopeng Tang.
• Department of Cardiovascular, The People's Hospital of Xuancheng City, Xuancheng City, Anhui Province, China; Department of Pacing Electrophysiology, Xinjiang Key Laboratory of Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi City, Xinjiang Uygur Autonomous Region, China.
• Clinics (Sao Paulo). 2024 Jan 1; 79: 100448100448.

ObjectivesTo study the complications and effectiveness of the treatment of chronic arrhythmias with cardiac Ganglion Plexus (GP) ablation, and to explore the value of the treatment of chronic arrhythmias with GP ablation.MethodsThis study was a one-arm interventional study of patients from the first hospital of Xinjiang Medical University and the People's Hospital of Xuancheng City admitted (09/2018-08/2021) because of bradyarrhythmia. The left atrium was modeled using the Carto3 mapping system. The ablation endpoint was the absence of a vagal response under anatomically localized and high-frequency stimulation guidance. Postoperative routine follow-up was conducted. Holter data at 3-, 6-, and 12-months were recorded.ResultsFifty patients (25 male, mean age 33.16 ± 7.89 years) were induced vagal response by either LSGP, LIGP, RAGP, or RIGP. The heart rate was stable at 76 bpm, SNRT 1.092s. DC, DR, HR, SDNN, RMSSD values were lower than that before ablation. AC, SSR, TH values were higher than those before ablation, mean heart rate and the slowest heart rate were significantly increased. There were significant differences in follow-up data between the preoperative and postoperative periods (all p < 0.05). All the patients were successfully ablated, and their blood pressure decreased significantly. No complications such as vascular damage, vascular embolism and pericardial effusion occurred.ConclusionsLeft Atrial GP ablation has good long-term clinical results and can be used as a treatment option for patients with bradyarrhythmia.Copyright © 2024 HCFMUSP. Published by Elsevier España, S.L.U. All rights reserved.

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