• Liqin Zhang, Mingjun Liu, Lutao Xie, and Xin Tian.
• Liqin Zhang is a resident physician in the Department of Intensive Care Medicine, Lishui Municipal Central Hospital, Lishui City, Zhejiang Province, China.
• Crit Care Nurse. 2024 Aug 1; 44 (4): 576257-62.

IntroductionThis is the first report of a patient who developed cardiogenic shock after receiving oral chemotherapy with capecitabine and was treated with venoarterial extracorporeal membrane oxygenation combined with continuous renal replacement therapy.Clinical FindingsA 58-year-old man developed an arrhythmia that rapidly progressed to cardiogenic shock and cardiac arrest after receiving oral capecitabine tablets to treat a rectal malignancy.InterventionsThe patient was treated with venoarterial extracorporeal membrane oxygenation in combination with continuous renal replacement therapy.OutcomeThe patient made a full recovery and was discharged from the hospital.ConclusionThe use of comprehensive supportive treatments such as extracorporeal membrane oxygenation combined with continuous renal replacement therapy in patients with capecitabine-induced cardiac arrest can rapidly reduce drug concentrations, eliminate harmful substances, and improve the prognosis.©2024 American Association of Critical-Care Nurses.

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