• Francisco Cartujano-Barrera, Lisa Sanderson Cox, Delwyn Catley, Xueya Cai, Francisco J Diaz, Evelyn Arana-Chicas, Arlette Chávez-Iñiguez, Chinwe Ogedegbe, Kristi D Graves, M Patricia Rivera, Arturo Ponce, Edward F Ellerbeck, and Ana Paula Cupertino.
• Department of Public Health Sciences, University of Rochester Medical Center, Rochester, NY. Electronic address: Francisco_Cartujano@URMC.Rochester.edu.
• Chest. 2024 Aug 10.

BackgroundLatino adults experience multiple barriers to health care access and treatment that result in tobacco-related disparities. Mobile interventions have the potential to deliver smoking cessation treatment among Latino adults, who show the highest use rates of mobile technologies.Research QuestionIs Decídetexto, a culturally accommodated mobile health intervention, more effective for smoking cessation compared with standard care among Latinx adults who smoke?Study Design And MethodsA two-arm parallel group randomized clinical trial was conducted in Kansas, New Jersey, and New York between October 2018 and September 2021. Eligible Latino adults who smoke (n = 457) were randomly assigned to Decídetexto or a standard care group. The primary outcome was biochemically verified 7-day smoking abstinence at week 24. Secondary outcomes included self-reported 7-day smoking abstinence at weeks 12 and 24 and uptake and adherence of nicotine replacement therapy (NRT).ResultsParticipants' mean age was 48.7 (SD, 11.1) years, 45.2% were female, and 50.3% smoked ≥ 10 cigarettes per day. Two hundred twenty-nine participants were assigned to Decídetexto and 228 to standard care. Treating those lost to follow-up as participants who continued smoking, 14.4% of participants in the Decídetexto group were biochemically verified abstinent at week 24 compared with 9.2% in the standard care group (OR, 1.66; 95% CI, 0.93-2.97; P = .09). Treating those lost to follow-up as participants who continued smoking, 34.1% of the participants in the Decídetexto group self-reported smoking abstinence at week 24 compared with 20.6% of participants in the standard care group (OR, 1.99; 95% CI, 1.31-3.03; P < .001). Analyzing only participants who completed the assessment at week 24, 90.6% (174/192) of participants in the Decídetexto group self-reported using NRT for at least 1 day compared with 70.2% (139/198) of participants in standard care (OR, 4.10; 95% CI, 2.31-7.28; P < .01).InterpretationAmong Latino adults who smoke, the Decídetexto intervention was not associated with a statistically significant increase in biochemically verified abstinence at week 24. However, the Decídetexto intervention was associated with a statistically significant increase in self-reported 7-day smoking abstinence at weeks 12 and 24 and uptake of NRT. This randomized clinical trial provides encouragement for the use of Decídetexto for smoking cessation among Latino adults.Clinical Trial RegistrationClinicalTrials.gov identifier: NCT03586596.Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.

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