• Francesca Battista, Silvia Bettini, Ludovica Verde, Luca Busetto, Luigi Barrea, and Giovanna Muscogiuri.
• Sports and Exercise Medicine Division, Regional Center for the therapeutic prescription of exercise in chronic disease, Department of Medicine, University of Padova, Via N. Giustiniani 2, 35128, Padova, Italy.
• Eur. J. Intern. Med. 2024 Aug 17.

AbstractObesity is a disease that is assuming pandemic proportions in recent decades. With the advancement of medicine and increased access to care, average survival has increased, resulting in a larger number of elderly people. As a result, the amount of elderly people living with obesity is increasing, and the morbidity and impact of obesity on ageing implies severe limitations for these people. The link between obesity and ageing is not only epidemiological, but also strictly pathophysiological. Obesity accelerates the ageing process and ageing is characterised by pathophysiological mechanisms shared by obesity itself. Some examples of alterations shared by ageing and obesity are metabolic changes, sarcopenia and reduced functional capacity related to both loss of muscle strength and reduced cardiorespiratory fitness, as well as a general reduction in the perception of quality of life. The specific ability to antagonize these mechanisms through non-pharmacological treatment based on nutrition and exercise has always been one of the focal points of the international literature. Therefore, this review provides the state of the art on scientific knowledge regarding the main effects of an adequate nutritional plan and an individualised exercise prescription on the general health of elderly with obesity. In particular, this paper addresses the effect of nutrition and physical exercise on pathophysiological changes peculiar of ageing and obesity, providing also the scientific rational for nutritional and exercise prescription in the population.Copyright © 2024 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

6 keywords...

hide…