• Leiliane Aparecida Diniz Tamashiro, José Maria Soares-Jr, Joel Renno, José Antônio Orellana Turri, Iara Moreno Linhares, Edmund Chada Baracat, and Nilson Roberto de Mello.
• Universidade de São Paulo, Hospital das Clinicas, Institute of Psychiatry, Faculty of Medicine, Women's Mental Health Program - São Paulo (SP), Brazil.
• Rev Assoc Med Bras (1992). 2024 Jan 1; 70 (7): e20231791e20231791.

ObjectiveThe aim of this study was to evaluate the effectiveness of cognitive behavioral therapy in the treatment of vasomotor, sexual dysfunction, and recurrent depression in postmenopausal women.MethodsThis prospective, open study evaluated 112 postmenopausal women with vasomotor symptoms. Sexual dysfunction has cultural, social, biological, and emotional issues and divided into two groups: G1, without depression (n=65) and G2, with recurrent depression (n=47). The subjects underwent 12 sessions of in-person cognitive behavioral therapy and 12 sessions of home-based activity over a period of 6 months. They were evaluated at 3 months following the completion of therapy. Depression, memory, and attention-related functions, as well as climactic symptoms, were assessed using a questionnaire.ResultsIn the depression questionnaire, the G1 group had a lower initial score than the G2 group (p<0.01). Following 6 months of therapy, both groups had similar improved scores. In the depression questionnaire, the women in group G1 had higher baseline values. In the assessment of vasomotor symptoms, the values in both groups were similar and showed an improvement in vasomotor symptoms after 24 weeks of treatment, but these effects disappeared after the follow-up of 48 weeks in the G2 group. Both groups improved the sexual dysfunction after 24 weeks.ConclusionCognitive behavioral therapy may be effective in reducing vasomotor symptoms and ameliorate the sexual dysfunction and recurrent depression in postmenopausal women after 24 weeks of treatment.

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