• DemirFulya AvcıFA0000-0003-0608-595XIstinye University, Department of Cardiology - İstanbul, Turkey.Medical Park Hospital, Department of Cardiology - Antalya, Turkey., İbrahim Ersoy, Ahmet Şeyda Yılmaz, Gökay Taylan, Emin Erdem Kaya, Ertan Aydın, Muammer Karakayalı, Muhammed Mürsel Öğütveren, Aybike Taşdelen Acar, and Şıho Hidayet.
• Istinye University, Department of Cardiology - İstanbul, Turkey.
• Rev Assoc Med Bras (1992). 2024 Jan 1; 70 (10): e20240508e20240508.

ObjectiveThe aim of our study was to determine the role of serum glucose-potassium ratio in predicting inhospital mortality in coronary care unit patients.MethodsThis study used data from the MORtality in CORonary Care Units in Turkey study, a national, observational, multicenter study that included all patients admitted to coronary care units between September 1, 2022, and September 30, 2022. Statistical analyses assessed the independent predictors of mortality. Two models were created. Model 1 included age, history of heart failure, chronic kidney disease, hypertension, diabetes mellitus, and coronary artery disease. Model 2 included glucose-potassium ratio in addition to these variables. Multivariate regression and receiver operating characteristic analysis were performed to compare Model 1 and Model 2 to identify if the glucose-potassium ratio is an independent predictor of inhospital mortality.ResultsIn a study of 3,157 patients, the mortality rate was 4.3% (n=137). Age (p=0.002), female gender (p=0.004), mean blood pressure (p<0.001), serum creatinine (p<0.001), C-reactive protein (p=0.002), white blood cell (p=0.002), and glucose-potassium ratio (p<0.001) were identified as independent predictors of mortality through multivariate regression analysis. The receiver operating characteristic analysis indicated that Model 2 had a statistically higher area under the curve than Model 1 (area under the curve 0.842 vs area under the curve 0.835; p<0.001). A statistically significant correlation was found between the inhospital mortality and glucose-potassium ratio (OR 1.015, 95%CI 1.006-1.024, p<0.001).ConclusionOur study showed that the glucose-potassium ratio may be a significant predictor of inhospital mortality in coronary care unit patients.

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