• Yuri Longato Boteon, Mariana Hollanda Martins da Rocha, Luciana Haddad, Rafael Antonio Arruda Pecora, Andre Dong Won Lee, Claudia Yang Santos, Amanda Pinter Carvalheiro da Silva Boteon, Igor Calil, Giovana Garcia Rossi, Fernanda Marques, Bianca Facas, and D'AlbuquerqueLuiz Augusto CarneiroLACHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil..
• Hospital Israelita Allbert Einstein, São Paulo, SP, Brazil.
• Clinics (Sao Paulo). 2024 Jan 1; 79: 100521100521.

IntroductionShort Bowel Syndrome (SBS) is a rare gastrointestinal disorder associated with Intestinal Failure (SBS-IF) that leads to morbidity, mortality, and a burden on healthcare costs. Intestine Transplantation (IT) is a treatment option for patients with SBS-IF as it replaces the missing or diseased intestine and offers the potential for return to normal activities and intestinal function. This study aims to describe the clinical course and demographical and clinical characteristics of subjects with SBS-IF who underwent IT in Brazil.MethodsThis retrospective observational study included all SBS-IF patients who underwent IT in two reference centers in Brazil from April 2011 to December 2021.ResultsA total of 7 young male participants were included in the study. The most frequent underlying condition was surgical complications, followed by intestinal volvulus and incisional hernia. The most frequent indication for IT was a hepatic disease associated with total Parenteral Nutrition (PN). The main type of IT performed was intestine only. The median time from underlying condition to IT was 67.3 (16.5‒88.5) months. The mean (SD) number of yearly hospitalizations per patient was 0.5 (0.3). The most common reason for hospitalization was PN-related complications. Sixty exams were performed in-hospital and 53 in the outpatient setting.ConclusionThe findings of this study may be helpful to understand better the journey of patients with SBS-IF to IT in Brazil, providing real-world evidence to develop health policy guidelines and improve the quality of life of these patients.Copyright © 2024. Published by Elsevier España, S.L.U.

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