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Case Reports
IgG4-related systemic disease presenting with lung entrapment and constrictive pericarditis.
- Hiroshi Sekiguchi, Ryohei Horie, James P Utz, and Jay H Ryu.
- Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN. Electronic address: sekiguchi.hiroshi@mayo.edu.
- Chest. 2012 Sep 1;142(3):781-3.
AbstractWe describe a 29-year-old woman who presented with chronic pleuropericarditis complicated by lung entrapment and constrictive pericarditis. Pleural biopsy performed during the decortication procedure revealed fibrinous pleuritis with lymphoplasmacytic inflammation including IgG4-positive plasma cells. The patient responded favorably to corticosteroid therapy with resolution of pleural effusion and constrictive physiology. To our knowledge, this is the first reported case of IgG4-related systemic disease manifesting as lung entrapment and constrictive pericarditis.
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