• Anesthesiology clinics · Sep 2011

    Review

    Voluven, a new colloid solution.

    • Anna Mizzi, Thanh Tran, Rachel Karlnoski, Ashley Anderson, Devanand Mangar, and Enrico M Camporesi.
    • Department of Cardiothoracic and Vascular Anesthesia, San Raffaele Hospital, "Vita e Salute" University, Milan, Italy.
    • Anesthesiol Clin. 2011 Sep 1;29(3):547-55.

    AbstractHydroxyethyl starch (HES) 130/0.4 (Voluven, Fresenius/Hospira, Germany) is indicated for the treatment and prophylaxis of hypovolemia. As the Voluven molecule is smaller than those of other available hydroxyethyl starch products, it is associated with less plasma accumulation and can be safely used in patients with renal impairment. Previous studies have demonstrated that Voluven has comparable effects on volume expansion and hemodynamics as other available HES products. Voluven is also associated with fewer effects on coagulation and may be an acceptable alternative to albumin for volume expansion in situations in which other starches are contraindicated secondary to risk of coagulopathy.Copyright © 2011 Elsevier Inc. All rights reserved.

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