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Ann Fr Anesth Reanim · May 2005
Review Case Reports[Value of skin tests for the choice of a neuromuscular blocking agent after an anaphylactic reaction].
- P Dewachter, C Mouton-Faivre, J-P Pertek, C Boudaa, and P-M Mertes.
- Service d'anesthésie-réanimation chirurgicale, CHU hôpital central, 29 avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy cedex, France. pascale.dewachter@wanadoo.fr
- Ann Fr Anesth Reanim. 2005 May 1;24(5):543-6.
AbstractWe report a grade III allergic hypersensitivity reaction occurring in a 72-year-old patient immediately after anaesthesia induction. Anaphylaxis to cisatracurium was diagnosed on clinical symptoms, biological tests and positivity of the cutaneous tests to this neuromuscular blocking agent. Five days after this allergological assessment, rocuronium, a muscle relaxant for which skin tests appeared negative was used during surgery without adverse effects. The authors underline the value of a detailed allergological assessment to identify the pathophysiologic mechanism, the culprit drug and to propose a safer alternate drug that might be used.
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