• Am J Psychiatry · Aug 1975

    Case Reports

    Amitriptyline-perphenazine overdose producing delayed hypomania in manic-depressive illness.

    • E J Mikkelsen and A H Rosebaum.
    • Am J Psychiatry. 1975 Aug 1;132(8):870-1.

    AbstractThe authors describe a 26-year-old woman who became hypomanic after awakening from a semicomatose state induced by an overdose of amitriptyline-perphenazine (Triavil). She had been depressed and had a strong family history of manic-depressive illness. The case is reported to support previous evidence that dopamine is a mediator for mania.

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