• Anaesthesia · Sep 1990

    Clinical Trial Controlled Clinical Trial

    Relief of injection pain in adults. EMLA cream for 5 minutes before venepuncture.

    • M R Nott and J L Peacock.
    • Department of Anaesthetics, Royal West Sussex Hospital, St Richard's, Chichester.
    • Anaesthesia. 1990 Sep 1;45(9):772-4.

    AbstractThe effectiveness of skin anaesthesia after 5 minutes' topical application of a lignocaine-prilocaine cream was evaluated. One hundred and twenty patients estimated the pain of antecubital venepuncture both on a linear scale and verbally after use of the cream for either 5 or 60 minutes, a placebo cream or no treatment. Reported pain was significantly less after only 5 minutes of the lignocaine-prilocaine cream (p = 0.002). The cream can be used to relieve the pain of all routine injections.

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