• Anesthesiology clinics · Dec 2010

    Review

    Sugammadex: cyclodextrins, development of selective binding agents, pharmacology, clinical development, and future directions.

    • Arezou Sadighi Akha, Joseph Rosa, Jonathan S Jahr, Alvin Li, and Kianusch Kiai.
    • UCLA JCCC Clinical Research Unit, 10945 Le Conte Avenue, 3360 PVUB, Los Angeles, CA 90095, USA.
    • Anesthesiol Clin. 2010 Dec 1;28(4):691-708.

    AbstractNeuromuscular blocking agents are widely used in perioperative medicine to aid in endotracheal intubation, facilitate surgery, and in critical care/emergency medicine settings. Muscle relaxants have profound clinical uses in current surgical and intensive care and emergency medical therapy. This article reviews cyclodextrins, development of selective binding agents, clinical development, and future directions of sugammadex.Copyright © 2010 Elsevier Inc. All rights reserved.

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