• Masui · Aug 2005

    Comparative Study

    [Appropriate dose of isobaric bupivacaine with fentanyl in spinal anesthesia for cesarean section].

    • Michiyo Kimoto, Kouhei Murao, Atsuko Shirane, Sachiyo Sakamoto, Makiko Yamada, Shin-ichi Nakao, and Koh Shingu.
    • Department of Anesthesiology, Kansai Medical University Hospital, Moriguchi 570-8506.
    • Masui. 2005 Aug 1;54(8):864-8.

    BackgroundSpinal anesthesia combined with fentanyl is commonly used for cesarean section. We studied the appropriate dose of isobaric bupivacaine for spinal anesthesia when combined with a fixed dose of 20 microg fentanyl.MethodsForty-seven women scheduled for cesarean section were allocated into four-groups according to the dose of 0.5% isobaric bupivacaine with 20 microg fentanyl; 1.0 ml (n=5), 1.5 ml (n=11), 2.0 ml (n=11), and 2.5 ml (n=20).ResultsThe requirement of epidural anesthesia for pain relief or muscle relaxant was less in the 2.0 ml and 2.5 ml groups than the other groups. However, dyspnea due to high spinal anesthesia developed in 3 subjects out of 20 in the 2.5 ml group.ConclusionsTwo ml of 0.5% isobaric bupivacaine was the most appropriate dose for cesarean section, when combined with 20 microg of fentanyl.

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