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Curr Opin Crit Care · Oct 2013
ReviewConservative initiation of antimicrobial treatment in ICU patients with suspected ICU-acquired infection: more haste less speed.
- Tjasa Hranjec and Robert G Sawyer.
- University of Virginia, Charlottesville, Virginia, USA.
- Curr Opin Crit Care. 2013 Oct 1; 19 (5): 461464461-4.
Purpose Of ReviewTo review the recent literature supporting the idea that in some patients suspected of having a new ICU-acquired infection, antibiotics can be withheld until evidence to confirm diagnosis is obtained.Recent FindingsRecent publications demonstrate that in community-acquired pneumonia, severe sepsis presenting to the emergency room, and suspected ICU-acquired infection, the time to antibiotic therapy does not necessarily seem to be a key determinant of outcome.SummaryIn the ICU, patients without septic shock but suspected of having an ICU-acquired infection may be able to have antibiotics withheld until infection is confirmed using a combination of laboratory, radiologic, and microbiological data.
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