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- S Boonen, D Vanderschueren, P Haentjens, and P Lips.
- Leuven University Center for Metabolic Bone Diseases, Katholieke Universiteit Leuven, Belgium. steven.boonen@uz.kuleuven.ac.be
- J. Intern. Med. 2006 Jun 1;259(6):539-52.
AbstractCombined calcium and vitamin D supplementation is an essential component of the management of osteoporosis, supported by a strong scientific rationale. The types of individuals who should receive calcium and vitamin D supplements are those: (i) patients with documented osteoporosis receiving antiresorptive or anabolic treatment; (ii) patients receiving glucocorticoids; and (iii) individuals with or at high risk of calcium and/or vitamin D insufficiencies, in particular older women and men. This article describes the evidence base that supports targeting these groups. Benefits are most apparent when 800 IU day(-1) vitamin D is complemented with a dose of 1000-1200 mg day(-1) elemental calcium. Compliance is also key to optimizing clinical efficacy.
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