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HSR Proc Intensive Care Cardiovasc Anesth · Jan 2010
Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning.
- G Berlot, A Vergolini, and C Calderan.
- Department of Anaesthesia and Intensive Care, Cattinara Hospital, University of Trieste, Italy.
- HSR Proc Intensive Care Cardiovasc Anesth. 2010 Jan 1;2(3):221-4.
AbstractEvidence of cardiovascular toxicity is present in the majority of tricyclic antidepressant overdoses. We report the case of a 63-year-old woman admitted to our department with a severe amitriptyline poisoning. The ECG at admission showed a pattern mimicking an acute anteroseptal subepicardial infarction. This pattern persisted for 11 days. Myocardial enzymes and echocardiographic findings never confirmed an ischemic event. At discharge, the ECG returned normal without cardiac or neurologic sequelae. Our experience suggest that after severe tricyclic antidepressant ingestion, ECG alterations resembling myocardial injury may occur early and last for a longer period than previously reported.
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